{"id":11053,"date":"2025-02-10T14:46:08","date_gmt":"2025-02-10T13:46:08","guid":{"rendered":"https:\/\/www.fgw-brandenburg.de\/person\/prof-dr-pablo-lorini\/"},"modified":"2026-05-07T15:02:10","modified_gmt":"2026-05-07T13:02:10","slug":"prof-dr-pablo-lorini","status":"publish","type":"person","link":"https:\/\/www.fgw-brandenburg.de\/en\/person\/prof-dr-pablo-lorini\/","title":{"rendered":"Prof. Dr. Pablo Villavicencio Lorini"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Professional Experience<\/h2>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>since 01\/2025: Head \/ Chief Physician of the Institute for Clinical Genetics, Brandenburg Medical School Theodor Fontane &amp; University Hospital Brandenburg an der Havel<\/li>\n\n\n\n<li>01\/2022-12\/2024: Deputy Head \/ Coordinator of the Center for Familial Breast and Ovarian Cancer, University Hospital Halle (Saale) &amp; Medical Director of Human Genetics at MVZ UKH gGmbH<\/li>\n\n\n\n<li>01\/2014-12\/2024: Deputy Director \/ Senior Consultant of the Institute of Human Genetics, University Hospital Halle (Saale)<\/li>\n\n\n\n<li>09\/2012-12\/2013: Specialist in Human Genetics, Center for Pediatric and Adolescent Medicine, Section of Pediatric Genetics, University Medical Center Freiburg<\/li>\n\n\n\n<li>07\/2011-08\/2012: Specialist in Human Genetics, Institute for Medical Genetics and Human Genetics &amp; MVZ, Charit\u00e9 Universit\u00e4tsmedizin Berlin<\/li>\n\n\n\n<li>02\/2005-07\/2011: Visiting Scientist, Research Group Development and Disease, Max Planck Institute for Molecular Genetics Berlin<\/li>\n\n\n\n<li>01\/2008-09\/2012: Teaching Coordinator of the Institute of Medical Genetics and Human Genetics, Charit\u00e9 Universit\u00e4tsmedizin Berlin<\/li>\n<\/ul>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">University Education<\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>02\/2005-07\/2011: Doctor in postgraduate training in human genetics, Institute of Medical Genetics and Human Genetics, Charit\u00e9 Universit\u00e4tsmedizin Berlin<\/li>\n\n\n\n<li>01\/2004-01\/2005: Doctor in postgraduate training in dermatology, Department of Dermatology and Venereology, Charit\u00e9 Universit\u00e4tsmedizin Berlin<\/li>\n\n\n\n<li>09\/2004: Doctorate, Institute for Molecular Biology and Biochemistry, Freie Universit\u00e4t Berlin<\/li>\n\n\n\n<li>10\/1996-12\/2003: Study of Human Medicine, Free University of Berlin<\/li>\n<\/ul>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Awards<\/h2>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>2011: Poster prize of the German Society for Human Genetics \/ GfH e.V.<\/li>\n<\/ul>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Plenary Lectures<\/h2>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>08\/2024: Hereditary tumor dispositions in the context of precision oncology and preventive medicine, Symposium for Precision Oncology, KKH UKH &amp; Leopoldina National Academy of Sciences, Halle (Saale)<\/li>\n\n\n\n<li>10\/2021: DOG Symposium Fr09 Childhood glaucoma &#8211; more than just eye pressure reduction, lecture: Clinical-genetic differential diagnostics of childhood glaucoma (online)<\/li>\n\n\n\n<li>06\/2013: Techniques of genetic diagnostics, 39th Annual Meeting of the Society for Neonatology and Pediatric Intensive Care Medicine (Freiburg i. Br.)<\/li>\n<\/ul>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Organization of Conferences and Lecture Series<\/h2>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>11\/2021: Training for cooperation partners of the Center for Familial Breast and Ovarian Cancer at the University Hospital Halle (Saale)<\/li>\n\n\n\n<li>06\/2016: 53rd Saxon-Thuringian Syndrome Conference &#8211; Halle (Saale)<\/li>\n\n\n\n<li>2014-2015: Case conferences of the Central German Competence Network for Rare Diseases (contact person for Halle)<\/li>\n\n\n\n<li>02\/2014: Patient information day, genetics of corneal diseases of the eye, Halle (Saale)<\/li>\n<\/ul>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Memberships in Committees (outside the MHB) and Professional Associations<\/h2>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>since 2025: Membership, European Society of Human Genetics \/ESHG<\/li>\n\n\n\n<li>since 2005: Membership, German Society of Human Genetics \/GfH e.V.<\/li>\n<\/ul>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Third-party Funded Projects (Selection)<\/h2>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<ul class=\"wp-block-list\">\n<li>2023-2024: Coordination of the certification of the FBREK center incl. HerediCaRe registry study at the University Hospital Halle as part of the German Consortium for Familial Breast and Ovarian Cancer (VdEK, BMBF)<\/li>\n\n\n\n<li>2018-2021: The Primary Cilium: An Organizing Center of Cellular Energy Homeostasis and Organismal Longevity (Wilhelm-Roux-Funding, MLU Halle-Wittenberg)<\/li>\n\n\n\n<li>2014-2016: OTUD3: function and clinical defects in ubiquitin dependent signaling (Wilhelm-Roux-Funding, MLU Halle-Wittenberg)<\/li>\n\n\n\n<li>2010-2012: Identification of genetic target factors for corneal tissue engineering (B. Braun Foundation)<\/li>\n<\/ul>\n\n\n\n<div style=\"height:60px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\">Publications (Selection)<\/h2>\n\n\n\n<div style=\"height:25px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><strong>Best 5:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Zachariae S, Quante AS, Kiechle M, Rhiem K, Fehm TN, Schr\u00f6der JG, Horvath J, Leinert E, Dikow N, Ronez J, Sch\u00f6nfeld M, van Mackelenbergh MT, Schatz UA, Meisel C, Aktas B, Witt D, Mehraein Y, Weber BHF, Solbach C, Speiser D, Hoyer J, Faigle-Krehl G, Much CD, Mueller-Rausch AV, <strong>Villavicencio-Lorini P<\/strong>, Banys-Paluchowski M, Pieh D, Schmutzler RK, Fischer C, Engel C. Calculating future 10-year breast cancer risks in risk-adapted surveillance: A method comparison and application in clinical practice. Cancer Prev Res (Phila). 2024 (PMID: 39575650) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39575650\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/39575650\/<\/a><\/li>\n\n\n\n<li>Liu H, Ding J, K\u00f6hnlein K, Urban N, Ori A, <strong>Villavicencio-Lorini P<\/strong>, Walentek P, Klotz LO, Hollemann T, Pfirrmann T. The GID Ubiquitin Ligase Complex is a Regulator of AMPK Activity and Organismal Lifespan. Autophagy. 2020 (PMID: 31795790) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31795790\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/31795790\/<\/a><\/li>\n\n\n\n<li>Kraya T, Quandt D, Pfirrmann T, Kindermann A, Lampe L, Schroeter ML, Kohlhase J, Stoevesandt D, Hoffmann K, <strong>Villavicencio-Lorini P<\/strong>. Functional characterization of a novel CSF1R mutation causing hereditary diffuse leukoencephalopathy with spheroids. Mol Genet Genomic Med. 2019 (PMID: 30729751) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/30729751\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/30729751\/<\/a><\/li>\n\n\n\n<li>Pfirrmann T, Emmerich D, Ruokonen P, Quandt D, Buchen R, Fischer-Zirnsak B, Hecht J, Krawitz P, Meyer P, Klopocki E, Stricker S, Lausch E, Seliger B, Hollemann T, Reinhard T, Auw-Haedrich C, Zabel B, Hoffmann K, <strong>Villavicencio-Lorini P<\/strong>. Molecular mechanism of CHRDL1-mediated X-linked megalocornea in humans and in Xenopus model. Hum Mol Genet. 2015 (PMID: 25712132) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25712132\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/25712132\/<\/a><\/li>\n\n\n\n<li><strong>Villavicencio-Lorini P<\/strong>, Kuss P, Friedrich J, Haupt J, Farooq M, T\u00fcrkmen S, Duboule D, Hecht J, Mundlos S. Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. J Clin Invest. 2010 (PMID: 20458143) <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/20458143\/\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/20458143\/<\/a><\/li>\n<\/ul>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p><strong>More\/all Publications:<\/strong><br>Pubmed: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Villavicencio-Lorini+P+OR+Lorini+P&amp;sort=date\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/pubmed.ncbi.nlm.nih.gov\/?term=Villavicencio-Lorini+P+OR+Lorini+P&amp;sort=date<\/a><br>ORCID: <a href=\"https:\/\/orcid.org\/0000-0002-4906-1539\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/orcid.org\/0000-0002-4906-1539<\/a><br>\u00a0<br>(in the future via MHB research database FactScience)<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-small-font-size\">Photo: Foto in Berlin (N. Karaarslan)<\/p>\n","protected":false},"featured_media":11027,"template":"","class_list":["post-11053","person","type-person","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Prof. Dr. Pablo Villavicencio Lorini | Fakult\u00e4t f\u00fcr Gesundheitswissenschaften<\/title>\n<meta name=\"description\" content=\"Personenvorstellung: Prof. Dr. Pablo Villavicencio Lorini\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.fgw-brandenburg.de\/en\/person\/prof-dr-pablo-lorini\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Prof. Dr. Pablo Villavicencio Lorini | Fakult\u00e4t f\u00fcr Gesundheitswissenschaften\" \/>\n<meta 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